Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BLM All Species: 13.03
Human Site: S460 Identified Species: 22.05
UniProt: P54132 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54132 NP_000048.1 1417 159000 S460 L N F S H L P S N S V S P G D
Chimpanzee Pan troglodytes XP_510594 1417 158822 S460 L N F S H L P S N S V S P G D
Rhesus Macaque Macaca mulatta XP_001097543 1416 158885 S459 L N F S H L P S N S V S P G D
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O88700 1416 158347 S465 L N S P Y L L S H S P S T E E
Rat Rattus norvegicus Q6AYJ1 621 69624
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515695 791 89186
Chicken Gallus gallus Q9I920 1142 126164 W241 E A S F N G S W C E K P T G K
Frog Xenopus laevis Q9DEY9 1364 152305 A430 V F K F N K L A V H D I G T K
Zebra Danio Brachydanio rerio XP_701357 1261 139417 G360 P L D Q S A K G L K G A D D A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGI8 1487 166060 S538 P D D F S P P S K Q N D P H L
Honey Bee Apis mellifera XP_396209 961 109321 V60 I D V I K S N V K E K D Y K S
Nematode Worm Caenorhab. elegans O18017 988 110641 P87 S S P P R Y R P S E N P G P S
Sea Urchin Strong. purpuratus XP_001175892 1394 152920 L464 L Q S T T K D L V P P P Q L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35187 1447 163819 L481 D T R S T I T L S Q N K N V Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 96.1 N.A. N.A. 76.9 21.2 N.A. 46.3 47.9 50.8 41.6 N.A. 27.8 30.9 26.5 31.5
Protein Similarity: 100 99.2 97.7 N.A. N.A. 85.2 30.9 N.A. 50.1 60.7 66.6 54 N.A. 47 47.1 40.2 47.6
P-Site Identity: 100 100 100 N.A. N.A. 40 0 N.A. 0 6.6 0 0 N.A. 20 0 0 6.6
P-Site Similarity: 100 100 100 N.A. N.A. 60 0 N.A. 0 13.3 20 6.6 N.A. 26.6 13.3 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 8 0 8 0 0 0 8 0 0 15 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 8 15 15 0 0 0 8 0 0 0 8 15 8 8 22 % D
% Glu: 8 0 0 0 0 0 0 0 0 22 0 0 0 8 8 % E
% Phe: 0 8 22 22 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 0 8 0 0 8 0 15 29 0 % G
% His: 0 0 0 0 22 0 0 0 8 8 0 0 0 8 0 % H
% Ile: 8 0 0 8 0 8 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 8 0 8 15 8 0 15 8 15 8 0 8 15 % K
% Leu: 36 8 0 0 0 29 15 15 8 0 0 0 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 29 0 0 15 0 8 0 22 0 22 0 8 0 0 % N
% Pro: 15 0 8 15 0 8 29 8 0 8 15 22 29 8 0 % P
% Gln: 0 8 0 8 0 0 0 0 0 15 0 0 8 0 8 % Q
% Arg: 0 0 8 0 8 0 8 0 0 0 0 0 0 0 0 % R
% Ser: 8 8 22 29 15 8 8 36 15 29 0 29 0 0 15 % S
% Thr: 0 8 0 8 15 0 8 0 0 0 0 0 15 8 0 % T
% Val: 8 0 8 0 0 0 0 8 15 0 22 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 8 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _